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Gludex IM/IV Injection
Dexamethasone Sodium Phosphate is used for Inflammatory conditions, Autoimmune conditions, Allergic or inflammatory conditions, Covid-19.
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✅ Description:
Dexamethasone 5mg/ml-
- Allergic states: Control of severe allergic conditions in asthma, dermatitis, drug reactions, allergic rhinitis, and serum sickness.
- Collagen disease: e.g., lupus erythematosus, rheumatoid arthritis.
- Dermatologic diseases: Bullous dermatitis, erythroderma, pemphigus, Stevens-Johnson syndrome.
- Endocrine disorders: Adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia in cancer, nonsuppurative thyroiditis.
- Gastrointestinal diseases: Regional enteritis, ulcerative colitis.
- Hematologic disorders: Hemolytic anemia, hypoplastic anemia, thrombocytopenic purpura.
- Neoplastic diseases: Leukemias, lymphomas.
- Nervous system: Acute exacerbations of multiple sclerosis, cerebral edema.
- Ophthalmic diseases: Temporal arteritis, uveitis, and ocular inflammatory conditions.
- Renal diseases: Inducing diuresis or remission of proteinuria in nephrotic syndrome.
- Respiratory diseases: Pulmonary tuberculosis, eosinophilic pneumonia, sarcoidosis.
- Rheumatic disorders: Short-term therapy for gouty arthritis, rheumatic carditis, arthritis, dermatomyositis, polymyositis, lupus erythematosus.
- Miscellaneous: Diagnostic testing of adrenocortical hyperfunction, trichinosis with neurologic involvement, tuberculous meningitis.
Safety Advices
Alcohol
CAUTION
Interaction with alcohol is unknown.
Pregnancy
CONSULT YOUR DOCTOR
- Inform your doctor if pregnant.
- Prescription based on benefits vs. risks.
Breastfeeding
CONSULT YOUR DOCTOR
- Inform your doctor if nursing.
- Prescription based on benefits vs. risks.
Driving
CAUTION
- May reduce mental awareness.
- Exercise caution.
Kidney
CAUTION
- Inform your doctor.
- Discuss your kidney condition with your doctor.
Liver
CAUTION
- Inform your doctor.
- Discuss your liver condition with your doctor.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Gludex IM/IV injection
- Allergic conditions
- Severe allergic reactions
- Asthma
- Cancer
- Rheumatic disorder
- Skin disorders
- Eye disorders
- Nephrotic syndrome
✔️ How does Gludex IM/IV injection work?
Gludex IM/IV is a steroid that works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.
✔️ Side Effects of Gludex IM/IV injection
Various adverse reactions are associated with prolonged use, including endocrine/metabolic, fluid/electrolyte disturbances, musculoskeletal effects, gastrointestinal effects, dermatological effects, CNS effects, ophthalmic effects, and immunosuppressive effects.
✔️ Quick Suggestions:
- Do not use it more often or for longer than advised by your doctor.
- Dexamethasone Injection may affect various laboratory tests.
- Dexamethasone can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
✔️ Indications
- Severe allergic conditions
- Collagen diseases
- Pulmonary disorders
- Blood disorders
- Rheumatic diseases
- Skin diseases
- Gastrointestinal disorders
- Oedema
- Eye disorders
- Neoplastic states
- Endocrine disorders
- Preoperative and postoperative support
- Treatment of COVID-19 in certain patients
✔️ Pharmacology
Dexamethasone is a synthetic glucocorticoid that decreases inflammation, inhibiting leukocyte migration and reducing capillary permeability. It suppresses the normal immune response.
✔️ Dosage & Administration of Gludex IM/IV injection
Given intravenously (IV), intramuscularly (IM), or locally. The dosage depends on the severity, usually 0.05-0.20 mg/kg for systemic therapy in adults.
✔️ Interaction
- Diuretics and/or cardiac glycosides.
- Antidiabetics.
- Non-steroidal anti-inflammatory drugs.
- Oral anticoagulants.
- Less effective with liver enzyme-inducing drugs.
✔️ Contraindications
- Gastric and duodenal ulcers.
- Systemic and ophthalmic fungal infections.
- Viral infections.
- Glaucoma.
- Hypersensitivity to corticosteroids.
✔️ Pregnancy & Lactation
Category C. Use during pregnancy only if benefits justify risks. Glucocorticoids appear in breast milk.
✔️ Precautions & Warnings
- Use the lowest possible dose.
- Caution in cardiovascular, endocrine, gastrointestinal, musculoskeletal, and neuropsychiatric conditions.
- Pediatric patients should be titrated to the lowest effective dose.
✔️ Storage Conditions
Below 30°C, protected from light. Do not freeze. Keep out of reach of children.
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here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
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everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
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